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Article

Conserved mammalian modularity of quantitative trait loci revealed human functional orthologs in blood pressure control.

PloS one - 1 Jan 2020

Deng Alan Y, Ménard Annie

Abstract excerpt

Genome-wide association studies (GWAS) have routinely detected human quantitative trait loci (QTLs) for complex traits. Viewing that most GWAS single nucleotide polymorphisms (SNPs) are found in non-coding regions unrelated to the physiology of a polygenic trait of interest, a vital question to answer is whether or not any of these SNPs can functionally alter the phenotype with which it is associated. The study...

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Identifiers

PMID: 32702059
DOI: 10.1371/journal.pone.0235756
PMCID: PMC7377405

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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