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Article

GARP: a key receptor controlling FOXP3 in human regulatory T cells.

Journal of cellular and molecular medicine - 1 Sept 2009

Probst-Kepper M, Geffers R, Kröger A, Viegas N, Erck C, Hecht H-J, Lünsdorf H, Roubin R, Moharregh-Khiabani D, Wagner K, Ocklenburg F, Jeron A, Garritsen H, Arstila T P, Kekäläinen E, Balling R, Hauser H, Buer J, Weiss S

Abstract excerpt

Recent evidence suggests that regulatory pathways might control sustained high levels of FOXP3 in regulatory CD4(+)CD25(hi) T (T(reg)) cells. Based on transcriptional profiling of ex vivo activated T(reg) and helper CD4(+)CD25(-) T (T(h)) cells we have identified GARP (glycoprotein-A repetitions predominant), LGALS3 (lectin, galactoside-binding, soluble, 3) and LGMN (legumain) as novel genes implicated in human...

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Source

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Identifiers

PMID: 19453521
DOI: 10.1111/j.1582-4934.2009.00782.x
PMCID: PMC4516490

Genes

FOXP3
LGALS3
LGMN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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