Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Regulatory T-cells: diverse phenotypes integral to immune homeostasis and suppression.

Toxicologic pathology - 1 Jan 2012

Peterson Richard A

Abstract excerpt

Regulatory T-cells (T(REG)) are diverse populations of lymphocytes that regulate the adaptive immune response in higher vertebrates. T(REG) delete autoreactive T-cells, induce tolerance, and dampen inflammation. T(REG) cell deficiency in humans (i.e., IPEX [Immunodysregulation, Polyendocrinopathy and Enteropathy, X-linked syndrome]) and animal models (e.g., "Scurfy" mouse) is associated with multisystemic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adaptive Immunity
Share to FOXP3 gene
Share to Homeostasis

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Phenotype

Share to T-Lymphocytes, Regulatory

Source

Identifiers

PMID: 22222887
DOI: 10.1177/0192623311430693

Genes

FOXP3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Regulatory T-cells: diverse phenotypes integral to immune homeostasis and suppression.PMID 22222887Read ↗

Regulatory T Cells: Concept, Classification, Phenotype, and Biological Characteristics.Semantic proximity Read ↗

Regulatory T cell function in autoimmune diseaseSemantic proximity Read ↗

Regulatory T cells: a review.Semantic proximity Read ↗

CD8+ regulatory T cells-A distinct T-cell lineage or a transient T-cell phenotype?Semantic proximity Read ↗

Regulatory T cells in human autoimmune diseases.Semantic proximity Read ↗

[T(H)17 lymphocytes: induction, phenotype, functions, and implications in human disease and therapy].Semantic proximity Read ↗

T cells in health and diseaseSemantic proximity Read ↗

Th17 and Treg cells, two new lymphocyte subpopulations with a key role in the immune response against infection.Semantic proximity Read ↗

Regulatory B cells in autoimmunity: developments and controversies.Semantic proximity Read ↗

Expanding Diversity and Common Goal of Regulatory T and B Cells. I: Origin, Phenotype, Mechanisms.Semantic proximity Read ↗

Intestinal Regulatory T Cells as Specialized Tissue-Restricted Immune Cells in Intestinal Immune Homeostasis and Disease.Semantic proximity Read ↗

CPHEN-016: Comprehensive phenotyping of human regulatory T cells.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.