Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Topics Community

Article

Regulatory T-cells: diverse phenotypes integral to immune homeostasis and suppression.

Toxicologic pathology - 1 Jan 2012

Peterson Richard A

Abstract excerpt

Regulatory T-cells (T(REG)) are diverse populations of lymphocytes that regulate the adaptive immune response in higher vertebrates. T(REG) delete autoreactive T-cells, induce tolerance, and dampen inflammation. T(REG) cell deficiency in humans (i.e., IPEX [Immunodysregulation, Polyendocrinopathy and Enteropathy, X-linked syndrome]) and animal models (e.g., "Scurfy" mouse) is associated with multisystemic...

Topics

Adaptive Immunity
Animals
Homeostasis
Humans
Mice
Phenotype
T-Lymphocytes, Regulatory

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 22222887
DOI: 10.1177/0192623311430693

Genes

FOXP3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Regulatory T-cells: diverse phenotypes integral to immune homeostasis and suppression.PMID 22222887Read ↗

Regulatory T Cells: Concept, Classification, Phenotype, and Biological Characteristics.Semantic proximity Read ↗

Regulatory T cell function in autoimmune diseaseSemantic proximity Read ↗

Regulatory T cells: a review.Semantic proximity Read ↗

CD8+ regulatory T cells-A distinct T-cell lineage or a transient T-cell phenotype?Semantic proximity Read ↗

Regulatory T cells in human autoimmune diseases.Semantic proximity Read ↗

[T(H)17 lymphocytes: induction, phenotype, functions, and implications in human disease and therapy].Semantic proximity Read ↗

T cells in health and diseaseSemantic proximity Read ↗

Th17 and Treg cells, two new lymphocyte subpopulations with a key role in the immune response against infection.Semantic proximity Read ↗

Regulatory B cells in autoimmunity: developments and controversies.Semantic proximity Read ↗

Expanding Diversity and Common Goal of Regulatory T and B Cells. I: Origin, Phenotype, Mechanisms.Semantic proximity Read ↗

Intestinal Regulatory T Cells as Specialized Tissue-Restricted Immune Cells in Intestinal Immune Homeostasis and Disease.Semantic proximity Read ↗

CPHEN-016: Comprehensive phenotyping of human regulatory T cells.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.