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Article

FOXP3 modifies the phenotypic and functional properties of regulatory T cells.

Nature reviews. Immunology - 1 Apr 2007

Campbell Daniel J, Ziegler Steven F

Abstract excerpt

In the periphery, tolerance to self antigens is mainly mediated by the CD4(+)CD25(+)FOXP3(+) subset of regulatory T cells, which can suppress the activity of autoreactive T cells that have escaped deletion in the thymus. The essential role of the transcription factor FOXP3 (forkhead box P3) in the development and function of these regulatory T cells has been well documented. It is also clear that regulatory T...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17380159
DOI: 10.1038/nri2061

Genes

FOXP3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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