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Article

Genotyping of K-ras codons 12 and 13 mutations in colorectal cancer by capillary electrophoresis.

Journal of chromatography. A - 26 Jun 2009

Chen Yen-Ling, Chang Ya-Sian, Chang Jan-Gowth, Wu Shou-Mei

Abstract excerpt

Point mutations of the K-ras gene located in codons 12 and 13 cause poor responses to the anti-epidermal growth factor receptor (anti-EGFR) therapy of colorectal cancer (CRC) patients. Besides, mutations of K-ras gene have also been proven to play an important role in human tumor progression. We established a simple and effective capillary electrophoresis (CE) method for simultaneous point mutation detection in...

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Identifiers

PMID: 19450806
DOI: 10.1016/j.chroma.2009.04.083

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EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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