Article
Analysis of single-strand conformation polymorphisms by capillary electrophoresis with laser induced fluorescence detection.
Journal of pharmaceutical and biomedical analysis - 1 Jun 1997
Arakawa H, Tsuji A, Maeda M, Kamahori M, Kambara H
Abstract excerpt
Detection of point mutations in genomic DNA is important for diagnosis of inherited characteristics and genetic diseases. A point mutation in a specific region of DNA amplified by polymerase chain reaction (PCR) can be detected with single-strand conformation polymorphism (SSCP) analysis. Analysis of SSCP by laser-induced fluorescence capillary electrophoresis in entangled polymer solution (CE-LIF) has been...
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