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Article

Analysis of single-strand conformation polymorphisms by capillary electrophoresis with laser induced fluorescence detection.

Journal of pharmaceutical and biomedical analysis - 1 Jun 1997

Arakawa H, Tsuji A, Maeda M, Kamahori M, Kambara H

Abstract excerpt

Detection of point mutations in genomic DNA is important for diagnosis of inherited characteristics and genetic diseases. A point mutation in a specific region of DNA amplified by polymerase chain reaction (PCR) can be detected with single-strand conformation polymorphism (SSCP) analysis. Analysi...

Topics

Codon
Electrophoresis, Capillary
Fluorescent Dyes
Genes, ras
Lasers
Mutation
Polymerase Chain Reaction
Polymorphism, Single-Stranded Conformational
Reproducibility of Results
Sensitivity and Specificity
Spectrometry, Fluorescence

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Spectrophotometry, Ultraviolet

Time Factors

Xanthenes

Source

Identifiers

PMID: 9226587
DOI: 10.1016/s0731-7085(96)01988-7

Genes

LIF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9226587-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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