Article
Simultaneous genotyping of multiplex single nucleotide polymorphisms of the K-ras gene with a home-made kit.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences - 25 Sept 2003
Zhao Chunxia, Xu Guowang, Shi Xianzhe, Ma Jianmei, Zhang Yan, Lv Shen, Yang Qing
Abstract excerpt
Accurate and fast genotyping of single nucleotide polymorphisms (SNPs) is important in the human genome project. Here an automated fluorescent method that can rapidly and accurately genotype multiplex known SNPs was developed by using a homemade kit, which has lower cost but higher resolution than commercial kit. With this method, oncogene K-ras was investigated, four known SNPs of K-ras gene exon 1 in 31...
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