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Frequency and spectrum of K-RAS codons 12 and 13 mutations in colorectal adenocarcinomas from Taiwan.

Cancer genetics and cytogenetics - 1 Apr 2005

Wu Chi-Ming, Tang Reiping, Wang Jeng-Yi, Changchien Chung-Rong, Hsieh Ling-Ling

Abstract excerpt

Mutations in codons 12 and 13 of the K-RAS oncogene are detected at a remarkably high frequency in colorectal adenocarcinoma and are believed to be a critical event in oncogenesis. In the present study, we evaluated colorectal tumor specimens from Taiwan for mutations in K-RAS codons 12 and 13 using polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) analysis and direct DNA sequencing....

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Identifiers

PMID: 15771905
DOI: 10.1016/j.cancergencyto.2004.08.030

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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