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Article

A human apoB100 transgenic mouse expresses human apoB100 in the RPE and develops features of early AMD.

Experimental eye research - 1 Jun 2009

Fujihara Masashi, Bartels Emil, Nielsen Lars B, Handa James T

Abstract excerpt

apoB100 lipoprotein particles have been found to accumulate in Bruch membrane prior to the development of age-related macular degeneration (AMD). This work was performed to determine whether mice that overexpress apoB100 in the RPE/choroid and liver develop landmarks of early AMD over time. Mice...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19450445
DOI: 10.1016/j.exer.2009.01.017
PMCID: PMC2729121

Genes

RPE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19450445-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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