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Article

Retinal ultrastructure of murine models of dry age-related macular degeneration (AMD).

Progress in retinal and eye research - 1 May 2010

Ramkumar Hema L, Zhang Jun, Chan Chi-Chao

Abstract excerpt

Age-related macular degeneration (AMD) is the most prevalent form of irreversible blindness worldwide in the elderly population. The pathology of dry AMD consists of macular degeneration of photoreceptors and the RPE, lipofuscin (A2E) accumulation, and drusen formation. Mice have been widely used for generating models that simulate human AMD features for investigating the pathogenesis, treatment and prevention of...

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Source

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Identifiers

PMID: 20206286
DOI: 10.1016/j.preteyeres.2010.02.002
PMCID: PMC2854213

Genes

RPE
ELOVL4

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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