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Article

Morphologic and electroretinographic phenotype of SR-BI knockout mice after a long-term atherogenic diet.

Investigative ophthalmology & visual science - 1 Aug 2009

Provost Alexandra C, Vede Leonie, Bigot Karine, Keller Nicole, Tailleux Anne, Jaïs Jean-Philipe, Savoldelli Michelle, Ameqrane Ilhame, Lacassagne Emmanuelle, Legeais Jean-Marc, Staels Bart, Menasche Maurice, Mallat Ziad, Behar-Cohen Francine, Abitbol Marc

Abstract excerpt

PURPOSE: To evaluate functional and ultrastructural changes in the retina of scavenger receptor B1 (SR-BI) knockout (KO) mice consuming a high fat cholate (HFC) diet. METHODS: Three-month-old male KO and wild-type (WT) mice were fed an HFC diet for 30 weeks. After diet supplementation, plasma cholesterol levels and electroretinograms were analyzed. Neutral lipids were detected with oil red O, and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19420333
DOI: 10.1167/iovs.08-2527

Genes

RPE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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