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Article

Correlation of UV-induced mutational spectra and the in vitro damage distribution at the human hprt gene.

Mutation research - 17 Jul 1998

Kotturi G, de Boer J G, Koop B F, Glickman B W

Abstract excerpt

We have determined the in vitro DNA damage distribution induced by 254 mm UV in the human hprt gene. The sequence-specific nature of the DNA damage for both main classes of UV-induced photoproducts, i.e., cyclobutane pyrimidine dimers (CPDs) and the pyrimidine <6-4> pyrimidone photoproducts (64PyPy), was evaluated. Utilizing an automated DNA sequencer plus auxiliary software, semi-automated analyses were...

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Identifiers

PMID: 9726024
DOI: 10.1016/s0027-5107(98)00085-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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