Article
Genotypic prediction of HIV-1 subtype D tropism.
Retrovirology - 13 Jul 2011
Raymond Stéphanie, Delobel Pierre, Chaix Marie-Laure, Cazabat Michelle, Encinas Stéphanie, Bruel Patrick, Sandres-Sauné Karine, Marchou Bruno, Massip Patrice, Izopet Jacques
Abstract excerpt
BACKGROUND: HIV-1 subtype D infections have been associated with rapid disease progression and phenotypic assays have shown that CXCR4-using viruses are very prevalent. Recent studies indicate that the genotypic algorithms used routinely to assess HIV-1 tropism may lack accuracy for non-B subtypes. Little is known about the genotypic determinants of HIV-1 subtype D tropism. RESULTS: We determined the HIV-1...
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