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Article

Interstitial flow regulates the angiogenic response and phenotype of endothelial cells in a 3D culture model.

Lab on a chip - 18 Oct 2016

Kim Sudong, Chung Minhwan, Ahn Jungho, Lee Somin, Jeon Noo Li

Abstract excerpt

A crucial yet ill-defined phenomenon involved in the remodeling of vascular networks, including angiogenic sprouting, is flow-mediated endothelial dynamics and phenotype changes. Despite interstitial flow (IF) being ubiquitously present in living tissues surrounding blood capillaries, it is rarely investigated and poorly understood how endothelial cells respond to this flow during morphogenesis. Here we develop a...

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Identifiers

PMID: 27722679
DOI: 10.1039/c6lc00910g

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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