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Article

Cadherin Expression Is Regulated by Mechanical Phenotypes of Fibroblasts in the Perivascular Matrix.

Cells, tissues, organs - 1 Jan 2024

Bala Vaishali, Patel Vidhi, Sewell-Loftin Mary Kathryn

Abstract excerpt

INTRODUCTION: The influence of mechanical forces generated by stromal cells in the perivascular matrix is thought to be a key regulator in controlling blood vessel growth. Cadherins are mechanosensors that facilitate and maintain cell-cell interactions and blood vessel integrity, but little is known about how stromal cells regulate cadherin signaling in the vasculature. Our objective was to investigate the...

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PMID: 38768571
DOI: 10.1159/000539319
PMCID: PMC11576492

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