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Article

Comparison of primary neuroblastoma tumors and derivative early-passage cell lines using genome-wide single nucleotide polymorphism array analysis.

Cancer research - 15 May 2009

Volchenboum Samuel L, Li Cheng, Li Shuli, Attiyeh Edward F, Reynolds C Patrick, Maris John M, Look A Thomas, George Rani E

Abstract excerpt

Stromal contamination is one of the major confounding factors in the analysis of solid tumor samples by single nucleotide polymorphism (SNP) arrays. As we propose to use genome-wide SNP microarray analysis as a diagnostic platform for neuroblastoma, the sensitivity, specificity, and accuracy of these studies must be optimized. To investigate the effects of stromal contamination, we derived early-passage cell...

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Identifiers

PMID: 19435921
DOI: 10.1158/0008-5472.CAN-08-3112
PMCID: PMC2739280

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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