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Article

Genome-wide analysis of neuroblastomas using high-density single nucleotide polymorphism arrays.

PloS one - 28 Feb 2007

George Rani E, Attiyeh Edward F, Li Shuli, Moreau Lisa A, Neuberg Donna, Li Cheng, Fox Edward A, Meyerson Matthew, Diller Lisa, Fortina Paolo, Look A Thomas, Maris John M

Abstract excerpt

BACKGROUND: Neuroblastomas are characterized by chromosomal alterations with biological and clinical significance. We analyzed paired blood and primary tumor samples from 22 children with high-risk neuroblastoma for loss of heterozygosity (LOH) and DNA copy number change using the Affymetrix 10K single nucleotide polymorphism (SNP) array. FINDINGS: Multiple areas of LOH and copy number gain were seen. The most...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 17327916
DOI: 10.1371/journal.pone.0000255
PMCID: PMC1797488

Genes

ALK
MYCN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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