Article
Tumor Touch Imprints as Source for Whole Genome Analysis of Neuroblastoma Tumors.
PloS one - 1 Jan 2016
Brunner Clemens, Brunner-Herglotz Bettina, Ziegler Andrea, Frech Christian, Amann Gabriele, Ladenstein Ruth, Ambros Inge M, Ambros Peter F
Abstract excerpt
INTRODUCTION: Tumor touch imprints (TTIs) are routinely used for the molecular diagnosis of neuroblastomas by interphase fluorescence in-situ hybridization (I-FISH). However, in order to facilitate a comprehensive, up-to-date molecular diagnosis of neuroblastomas and to identify new markers to refine risk and therapy stratification methods, whole genome approaches are needed. We examined the applicability of an...
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