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Article

Expression of a transgene encoding mutant p193/CUL7 preserves cardiac function and limits infarct expansion after myocardial infarction.

Heart (British Cardiac Society) - 1 Jul 2009

Hassink R J, Nakajima H, Nakajima H O, Doevendans P A, Field L J

Abstract excerpt

BACKGROUND: Transgenic mice expressing the dominant interfering p193 protein in cardiomyocytes (MHC-1152stop mice) exhibit an induction of cell cycle activity and altered remodelling after experimental myocardial infarction (MI). OBJECTIVE: To determine whether the altered remodelling results in improved cardiac function in the MHC-1152stop mice after MI, as compared with non-transgenic mice. METHODS:...

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Identifiers

PMID: 19435717
DOI: 10.1136/hrt.2008.150128
PMCID: PMC3020667

Genes

CUL7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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