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Article

Role of IQGAP1 in Carcinogenesis

4 Aug 2021

Abstract excerpt

Scaffolding proteins can play important roles in cell signaling transduction. IQ motif-containing GTPase-activating protein 1 (IQGAP1) influences many cellular activities by scaffolding multiple key signaling pathways, including ones involved in carcinogenesis. Two decades of studies provide evidence that IQGAP1 plays an essential role in promoting cancer development. IQGAP1 is overexpressed in many types of...

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PMID: 34439095
DOI: 10.3390/cancers13163940

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