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Reduced expression of IQGAP2 and higher expression of IQGAP3 correlates with poor prognosis in cancers

26 Oct 2017

Abstract excerpt

IQGAPs is a family of proteins which comprises three members, in humans. The expression pattern and role of IQGAP1 has been well established in many cancers, whereas those of IQGAP2 and IQGAP3, have mostly remained unexplored. We used available large datasets, to explore the pan-cancer status of these two genes in-silico. Here we have analysed their mRNA expression and correlation with survivability in eight...

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PMID: 29073199
DOI: 10.1371/journal.pone.0186977

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