Article
Serotonin-2A receptor and catechol-O-methyltransferase polymorphisms in panic disorder.
Progress in neuro-psychopharmacology & biological psychiatry - 10 Jan 2012
Karacetin Gul, Bayoglu Burcu, Cengiz Mujgan, Demir Turkay, Kocabasoglu Nese, Uysal Omer, Bayar Reha, Balcioglu Ibrahim
Abstract excerpt
Catechol-O-methyltransferase (COMT) and serotonin receptor 2A (5HTR2A) polymorphisms have been investigated for their possible role in panic disorder (PD). The aim of this study was to investigate the genotype distribution of the COMT val158met and 5HTR2A 102T/C polymorphisms in PD. COMT val158met is a polymorphism at codon 158 that results in variations in COMT enzymatic activity with high- (H) and low-activity...
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