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Article

Variants in ST8SIA1 do not play a major role in susceptibility to multiple sclerosis in Canadian families.

Journal of neuroimmunology - 25 Jul 2009

Ramagopalan Sreeram V, Morrison Katie M, Para Andrea, Handel Adam, Disanto Giulio, Handunnetthi Lahiru, Orton Sarah M, Sadovnick A Dessa, Ebers George C

Abstract excerpt

Multiple sclerosis (MS) is a complex trait with a significant genetic component. Recent work has implicated the ST8SIA1 gene, encoding a ganglioside synthase, in susceptibility to the disease, perhaps with a parent-of-origin effect. In this investigation of 1318 MS patients from 756 Canadian families, we analysed the transmission of the four single nucleotide polymorphisms in ST8SIA previously shown to be...

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Source

Identifiers

PMID: 19428123
DOI: 10.1016/j.jneuroim.2009.04.017

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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