Article
Familial clustering of multiple sclerosis in a Dutch genetic isolate.
Multiple sclerosis (Houndmills, Basingstoke, England) - 1 Jan 2007
Hoppenbrouwers I A, Cortes L M Pardo, Aulchenko Y S, Sintnicolaas K, Njajou O, Snijders P J L M, Oostra B A, van Duijn C M, Hintzen R Q
Abstract excerpt
Multiple sclerosis (MS) is a complex disease with a substantial, yet poorly identified, genetic influence. We estimated the pattern of familial aggregation of MS in a recent genetically isolated population in The Netherlands. Forty-eight MS patients were identified. Their relationship was evaluated by tracing extended pedigrees, making use of municipal and church records. Of the 48 MS patients, 24 could be linked...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.