Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

HLA-DQ polymorphisms do not explain HLA class II associations with multiple sclerosis in two Canadian patient groups.

Neurology - 1 Jun 1993

Haegert D G, Francis G S

Abstract excerpt

Patient sharing of HLA-DQ allelic polymorphisms is a possible explanation for the association of multiple sclerosis (MS) with different HLA class II haplotypes in different populations. We used two-locus linkage analysis to investigate the relevance of three different polymorphisms to MS suscepti...

Topics

Alleles
France
Genes, MHC Class II
Genetic Linkage
HLA-DQ Antigens
Haplotypes
Humans
Multiple Sclerosis
Nova Scotia
Polymorphism, Genetic
Polymorphism, Restriction Fragment Length
Quebec

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 7909591
DOI: 10.1212/wnl.43.6.1207

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7909591-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

HLA-DQ polymorphisms do not explain HLA class II associations with multiple sclerosis in two Canadian patient groups.PMID 7909591Read ↗

HLA-DQA1 and -DQB1 associations with multiple sclerosis in Sardinia and French Canada: evidence for immunogenetically distinct patient groups.Semantic proximity Read ↗

Multiple sclerosis in French Canadians: evidence for HLA class II susceptibility and resistance genes.Semantic proximity Read ↗

A predominant role for the HLA class II region in the association of the MHC region with multiple sclerosis.Semantic proximity Read ↗

No association between susceptibility to multiple sclerosis and HLA-DPB1 alleles in the French Canadian population.Semantic proximity Read ↗

Contribution of a single DQ beta chain residue to multiple sclerosis in French Canadians.Semantic proximity Read ↗

Epistasis among HLA-DRB1, HLA-DQA1, and HLA-DQB1 loci determines multiple sclerosis susceptibility.Semantic proximity Read ↗

Genetic susceptibility to MS: a second stage analysis in Canadian MS families.Semantic proximity Read ↗

Association of susceptibility to multiple sclerosis in Southern Han Chinese with HLA-DRB1, -DPB1 alleles and DRB1-DPB1 haplotypes: distinct from other populations.Semantic proximity Read ↗

HLA-DR, -DQA1 and -DQB1 associations in Australian multiple sclerosis patients.Semantic proximity Read ↗

Genetic susceptibility to multiple sclerosis in a Shanghai Chinese population. The role of the HLA class II genes.Semantic proximity Read ↗

Mapping multiple sclerosis susceptibility to the HLA-DR locus in African Americans.Semantic proximity Read ↗

Genetic analysis of vitamin D related genes in Canadian multiple sclerosis patients. Canadian Collaborative Study Group.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.