Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

NR1H3 p.Arg415Gln Is Not Associated to Multiple Sclerosis Risk.

Neuron - 19 Oct 2016

Abstract excerpt

A recent study by Wang et al. (2016a) claims that the low-frequency variant NR1H3 p.Arg415Gln is sufficient to cause multiple sclerosis in certain individuals and determines a patient's likelihood of primary progressive disease. We sought to replicate this finding in the International MS Genetics Consortium (IMSGC) patient collection, which is 13-fold larger than the collection of Wang et al. (2016a), but we find...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Multiple Sclerosis
Share to Mutation
Share to Polymorphism, Single Nucleotide

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Open in PubMed Open full text

Identifiers

PMID: 27764667
DOI: 10.1016/j.neuron.2016.09.052
PMCID: PMC5641967

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

NR1H3 p.Arg415Gln Is Not Associated to Multiple Sclerosis Risk.PMID 27764667Read ↗

<i>NR1H3</i> p.Arg415Gln Is Not Associated To Multiple Sclerosis RiskSemantic proximity Read ↗

Case-Control Studies Are Not Familial Studies.Semantic proximity Read ↗

Genetic variants regulate NR1H3 expression and contribute to multiple sclerosis risk.Semantic proximity Read ↗

Nuclear Receptor NR1H3 in Familial Multiple Sclerosis.Semantic proximity Read ↗

No evidence of association of the rare nsSNP rs35667974 in IFIH1 with multiple sclerosis.Semantic proximity Read ↗

MS susceptibility is not affected by single nucleotide polymorphisms in the MMP9 gene.Semantic proximity Read ↗

Editorial Note to:Nuclear Receptor NR1H3 in Familial Multiple Sclerosis.Semantic proximity Read ↗

Closing the case of APOE in multiple sclerosis: no association with disease risk in over 29 000 subjects.Semantic proximity Read ↗

Multiple sclerosis susceptibility loci do not alter clinical and MRI outcomes in clinically isolated syndrome.Semantic proximity Read ↗

Analysis of NOD-like receptor NLRP1 in multiple sclerosis families.Semantic proximity Read ↗

Genetic variation in nitric oxide synthase 2A (NOS2A) and risk for multiple sclerosis.Semantic proximity Read ↗

The repeat variant in MSH3 is not a genetic modifier for spinocerebellar ataxia type 3 and Friedreich's ataxia.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.