Article
Genotypes at the APOE and SCA2 loci do not predict the course of multiple sclerosis in patients of Portuguese origin.
Multiple sclerosis (Houndmills, Basingstoke, England) - 1 Apr 2004
Santos Mónica, Costa Maria do Carmo, Edite Rio Maria, José Sá Maria, Monteiro Marta, Valença Angela, Sá Alfredo, Dinis José, Figueiredo José, Bigotte de Almeida Luís, Valongueiro António, Coelho Isabel, Matamá Maria Teresa, Pinto-Basto Jorge, Sequeiros Jorge, Maciel Patrícia
Abstract excerpt
Multiple sclerosis (MS) is a demyelinating disease that affects about one in 500 young Europeans. In order to test the previously proposed influence of the APOE and SCA2 loci on susceptibility to MS, we studied these loci in 243 Portuguese patients and 192 healthy controls and both parents of 92 patients. We did not detect any significant difference when APOE and SCA2 allele frequencies of cases and controls were...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.