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Article

Genetic variation in the SST gene and its receptors in relation to circulating levels of insulin-like growth factor-I, IGFBP3, and prostate cancer risk.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 May 2009

Johansson Mattias, McKay James D, Wiklund Fredrik, Rinaldi Sabina, Hallmans Göran, Bälter Katarina, Adami Hans-Olov, Grönberg Henrik, Stattin Pär, Kaaks Rudolf

Abstract excerpt

BACKGROUND: Somatostatin (SST) and its receptors (SSTR1-5) may have a role in prostate cancer by influencing the IGFI hormone axis or through direct effects on prostate epithelia. We have investigated if genetic variation in the SST and SSTR1-5 genes influences prostate cancer risk and/or circulating IGFI and IGFBP3 hormone levels. MATERIALS AND METHODS: We analyzed 28 haplotype tagging single nucleotide...

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Source

Identifiers

PMID: 19423539
DOI: 10.1158/1055-9965.EPI-08-0893

Genes

IGFBP3
SST
CAPS
SSTR1
SSTR5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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