Article
Association between somatostatin receptor 5 gene polymorphisms and pancreatic cancer risk and survival.
Cancer - 1 Jul 2011
Li Donghui, Tanaka Motofumi, Brunicardi F Charles, Fisher William E, Gibbs Richard A, Gingras Marie-Claude
Abstract excerpt
BACKGROUND: Somatostatin (SST) inhibited cell proliferation and negatively regulated the release of growth hormones by means of specific receptors (SSTR). Genetic variation in SSTR had been associated with risk of human cancers but had never been investigated in pancreatic cancer. METHODS: In this retrospective study the SSTR5 gene in paired tumor and blood samples from 33 pancreatic adenocarcinoma patients using...
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