Article
Analysis of somatostatin receptors 2 and 5 polymorphisms in patients with acromegaly.
The Journal of clinical endocrinology and metabolism - 1 Aug 2005
Filopanti M, Ronchi C, Ballarè E, Bondioni S, Lania A G, Losa M, Gelmini S, Peri A, Orlando C, Beck-Peccoz P, Spada A
Abstract excerpt
OBJECTIVE: The aim of the study was to investigate the possible correlation of single nucleotide polymorphisms in somatostatin receptor (SSTR)2 and SSTR5 genes with the responsiveness to somatostatin analogs in a cohort of acromegalic patients. STUDY DESIGN: Three single nucleotide polymorphisms (a-83 g, c-57 g, and t80c) of SSTR2 and three (t-461c, c325t, and c1004t) of SSTR5 were analyzed in 66 acromegalic...
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