Article
Pituitary Adenoma: SSTR2 rs2236750, SSTR5 rs34037914, and AIP rs267606574 Genetic Variants, Serum Levels, and Ki-67 Labeling Index Associations.
Medicina (Kaunas, Lithuania) - 1 Aug 2024
Gedvilaite-Vaicechauskiene Greta, Kriauciuniene Loresa, Tamasauskas Arimantas, Rovite Vita, Mandrika Ilona, Wu Sheng-Nan, Huang Chin-Wei, Poskiene Lina, Liutkeviciene Rasa
Abstract excerpt
Background and Objectives: This study explores the complex pathogenesis of pituitary adenomas (PAs), prevalent intracranial tumors in the pituitary gland. Despite their generally benign nature, PAs exhibit a diverse clinical spectrum involving hormone hypersecretion and varying invasiveness, hinting at multifaceted molecular mechanisms and abnormalities in tumorigenesis and gene regulation. Materials and Methods:...
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