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Article

ABCB1 gene polymorphisms and haplotype analysis in colorectal cancer.

International journal of colorectal disease - 1 Aug 2009

Panczyk Mariusz, Balcerczak Ewa, Piaskowski Sylwester, Jamroziak Krzysztof, Pasz-Walczak Grazyna, Mirowski Marek

Abstract excerpt

PURPOSE: The aim of this study was to determine the significance of three most common single-nucleotide polymorphisms (SNPs) of ABCB1 gene in the development of colorectal cancer and to estimate the influence of these SNPs to surviving patients' treatment combination adjuvant therapy 5-fluorouracil/leucovorin. Haplotype structure of ABCB1 was analysed, and degree of linkage disequilibrium (LD) between SNPs of...

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Source

Identifiers

PMID: 19415305
DOI: 10.1007/s00384-009-0724-0

Genes

ABCB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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