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Article

ABCB1/MDR1 gene polymorphism and colorectal cancer risk: a meta-analysis of case-control studies.

Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland - 1 Jan 2013

He T, Mo A, Zhang K, Liu L

Abstract excerpt

AIM: ABCB1/MDR1 protein is found in high concentrations on the apical surfaces of colonic epithelial cells. It acts as an efflux pump by transporting toxic endogenous substances, drugs and xenobiotics out of cells. Polymorphisms in the ABCB1/MDR1 gene may either change expression of the ABCB1/MDR1 protein or alter its function, suggesting its possible association with colorectal cancer. Several studies have...

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Identifiers

PMID: 23279665
DOI: 10.1111/j.1463-1318.2012.02919.x

Genes

ABCB1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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