Article
The association between genetic variants in the genes for cytochrome P450 B1 and ATP-binding cassette transporter genes and breast cancer risk.
Molecular biology reports - 1 Aug 2020
ShahidSales Soodabeh, Mehramiz Mehrane, Radmanesh Davood, Rastgar-Moghadam Azam, Hassanian Seyed Mahdi, Khazaei Majid, Ghazizade Hamideh, Ferns Gordon A, Avan Amir
Abstract excerpt
Breast cancer is among the most common malignancies in women. Recent studies have shown that polymorphisms in genes involved in the metabolism and transport of anticancer drugs are associated with outcomes of several malignancies, e.g., breast cancer. In this study we evaluate whether CYP1B1/rs1056836 and ABCB1/rs2032582 gene variants are associated with breast cancer. Eighty eight cases and 200 controls, were...
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