Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Interaction between genetic polymorphisms and stressful life events in first episode depression.

Journal of affective disorders - 1 Dec 2009

Bukh Jens Drachmann, Bock Camilla, Vinberg Maj, Werge Thomas, Gether Ulrik, Vedel Kessing Lars

Abstract excerpt

BACKGROUND: A polymorphism in the serotonin transporter (5-HTT) gene seems to moderate the influence of stressful life events on depression. However, the results from previous studies of gene-environment interactions in depression are inconsistent and might be confounded by the history of depress...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Brain-Derived Neurotrophic Factor
Share to Depressive Disorder
Share to Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Life Change Events

Share to Polymorphism, Genetic

Share to Polymorphism, Single Nucleotide

Share to Serotonin Plasma Membrane Transport Proteins

Share to Socioeconomic Factors

Source

Identifiers

PMID: 19339052
DOI: 10.1016/j.jad.2009.02.023

Genes

HTT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19339052-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Interaction between genetic polymorphisms and stressful life events in first episode depression.PMID 19339052Read ↗

No interactions between genetic polymorphisms and stressful life events on outcome of antidepressant treatment.Semantic proximity Read ↗

The relationship between stressful life events, the serotonin transporter (5-HTTLPR) genotype and major depression.Semantic proximity Read ↗

Influence of life stress on depression: moderation by a polymorphism in the 5-HTT gene.Semantic proximity Read ↗

[Genetics and stressful life events interact in depression].Semantic proximity Read ↗

Interaction between the serotonin transporter gene (5-HTTLPR), stressful life events, and risk of depression: a meta-analysis.Semantic proximity Read ↗

Life events, first depression onset and the serotonin transporter gene.Semantic proximity Read ↗

Interaction between serotonin transporter gene, catechol-O-methyltransferase gene and stressful life events in mood disorders.Semantic proximity Read ↗

Current developments and controversies: does the serotonin transporter gene-linked polymorphic region (5-HTTLPR) modulate the association between stress and depression?Semantic proximity Read ↗

Gene-environment interactions predict cortisol responses after acute stress: implications for the etiology of depression.Semantic proximity Read ↗

Gene-environment interactions in depression research: genetic polymorphisms and life-stress polyprocedures.Semantic proximity Read ↗

No association between the serotonin-1A receptor gene single nucleotide polymorphism rs6295C/G and symptoms of anxiety or depression, and no interaction between the polymorphism and environmental stressors of childhood anxiety or recent stressful life events on anxiety or depression.Semantic proximity Read ↗

Interactions between life stressors and susceptibility genes (5-HTTLPR and BDNF) on depression in Korean elders.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.