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Article

Interaction between the serotonin transporter gene (5-HTTLPR), stressful life events, and risk of depression: a meta-analysis.

JAMA - 17 Jun 2009

Risch Neil, Herrell Richard, Lehner Thomas, Liang Kung-Yee, Eaves Lindon, Hoh Josephine, Griem Andrea, Kovacs Maria, Ott Jurg, Merikangas Kathleen Ries

Abstract excerpt

CONTEXT: Substantial resources are being devoted to identify candidate genes for complex mental and behavioral disorders through inclusion of environmental exposures following the report of an interaction between the serotonin transporter linked polymorphic region (5-HTTLPR) and stressful life events on an increased risk of major depression. OBJECTIVE: To conduct a meta-analysis of the interaction between the...

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Identifiers

PMID: 19531786
DOI: 10.1001/jama.2009.878
PMCID: PMC2938776

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Interaction between the serotonin transporter gene (5-HTTLPR), stressful life events, and risk of depression: a meta-analysis.PMID 19531786Read ↗

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