Article
Depression, Stressful Life Events, and the Impact of Variation in the Serotonin Transporter: Findings from the National Longitudinal Study of Adolescent to Adult Health (Add Health).
PloS one - 1 Jan 2016
Haberstick Brett C, Boardman Jason D, Wagner Brandon, Smolen Andrew, Hewitt John K, Killeya-Jones Ley A, Tabor Joyce, Halpern Carolyn T, Brummett Beverly H, Williams Redford B, Siegler Ilene C, Hopfer Christian J, Mullan Harris Kathleen
Abstract excerpt
BACKGROUND: The low transcriptionally efficient short-allele of the 5HTTLPR serotonin transporter polymorphism has been implicated to moderate the relationship between the experience of stressful life events (SLEs) and depression. Despite numerous attempts at replicating this observation, results remain inconclusive. METHODS: We examined this relationship in young-adult Non-Hispanic white males and females...
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