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Article

Variants in the coagulation factor 2 receptor (F2R) gene influence the risk of myocardial infarction in men through an interaction with interleukin 6 serum levels.

Thrombosis and haemostasis - 1 May 2009

Gigante Bruna, Vikström Max, Meuzelaar Linda Strömqvist, Chernogubova Ekaterina, Silveira Angela, Hooft Ferdinand Van't, Hamsten Anders, de Faire Ulf

Abstract excerpt

Thrombin-activated factor 2 receptor (F2R) links thrombosis to inflammation modulating interleukin (IL)6 synthesis. We have investigated the role of F2R genetic variants and their interaction with IL6 serum levels in the occurrence of myocardial infarction (MI) in the Stockholm Heart Epidemiology...

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PMID: 19404549

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19404549-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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