Article
Interleukin-6 gene polymorphisms and susceptibility to myocardial infarction: the ECTIM study. Etude Cas-Témoin de l'Infarctus du Myocarde.
Journal of molecular medicine (Berlin, Germany) - 1 Jun 2001
Georges J L, Loukaci V, Poirier O, Evans A, Luc G, Arveiler D, Ruidavets J B, Cambien F, Tiret L
Abstract excerpt
There is growing evidence that interleukin (IL) 6 plays an important role in the atherosclerotic process because of its role in mediating immune and inflammatory responses and inducing cell proliferation. The present study examined whether molecular variations at the IL-6 locus are involved in the predisposition to myocardial infarction. The entire coding region, 1,158 bp of the 5' flanking region and 237 bp of...
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