Article
Variation in inflammation-related genes and risk of incident nonfatal myocardial infarction or ischemic stroke.
Atherosclerosis - 1 May 2008
Bis Joshua C, Heckbert Susan R, Smith Nicholas L, Reiner Alexander P, Rice Kenneth, Lumley Thomas, Hindorff Lucia A, Marciante Kristin D, Enquobahrie Daniel A, Monks Stephanie A, Psaty Bruce M
Abstract excerpt
BACKGROUND: From initiation to plaque rupture, immune system components contribute to atherosclerosis. We investigated variation in inflammation-related genes - interleukin (IL)-1beta, IL-6, C-reactive protein (CRP), IL-10, IL-18, and the tumor necrosis factor (TNF) superfamily [lymphotoxin(LT)-alpha, TNF-alpha, LT-beta] - with respect to nonfatal incident myocardial infarction (MI) or ischemic stroke risk....
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