Interleukin-6 serum levels and genotypes influence the risk for myocardial infarction.

doi:10.1016/j.atherosclerosis.2003.08.029

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Article

Interleukin-6 serum levels and genotypes influence the risk for myocardial infarction.

Atherosclerosis - 1 Dec 2003

Bennet Anna M, Prince Jonathan A, Fei Guo Zhong, Lyrenäs Louise, Huang YiHui, Wiman Björn, Frostegård Johan, Faire Ulf de

Abstract excerpt

OBJECTIVE: Several studies show that the inflammatory component in atherosclerosis may contribute to increased risk for cardiovascular disease (CVD). Interleukin-6 (IL-6) is a key pro-inflammatory and immune-stimulatory cytokine of presumed importance for CVD and the metabolic syndrome. METHODS AND RESULTS: In this case-control study, 1179 surviving myocardial infarction (MI) cases and 1528 healthy controls were...

Topics

C-Reactive Protein
Case-Control Studies
Cohort Studies
Female
Genetic Markers
Genotype
Humans
Incidence
Interleukin-6
Male
Myocardial Infarction
Reference Values
Risk Assessment
Sensitivity and Specificity

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Open in PubMed

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PMID: 14644408
DOI: 10.1016/j.atherosclerosis.2003.08.029

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