Article
Plasma fibrinogen concentration predicts the risk of myocardial infarction differently in various parts of Europe: effects of beta-fibrinogen genotype and environmental factors. The HIFMECH Study.
Thrombosis and haemostasis - 1 Dec 2004
Mannila Maria Nastase, Silveira Angela, Hawe Emma, Eriksson Per, Aillaud Marie Françoise, Juhan-Vague Irene, Yudkin John, Margaglione Maurizio, di Minno Giovanni, Mussoni Luciana, Tremoli Elena, Humphries Steve, Hamsten Anders
Abstract excerpt
The propensity to atherothrombotic disease differs in Europe, with high-risk regions located in the North of Europe and lowrisk regions in the South of Europe. The HIFMECH study (Hypercoagulability and Impaired Fibrinolytic function MECHanisms predisposing to myocardial infarction (MI) study) was undertaken to elucidate genetic and environmental mechanisms underlying MI based on investigations of postinfarction...
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