Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The role of genetic variation in the lamin a/c gene in the etiology of polycystic ovary syndrome.

The Journal of clinical endocrinology and metabolism - 1 Jul 2009

Urbanek Margrit, Nampiaparampil Geetha, D'Souza Janine, Sefton Elizabeth, Ackerman Christine, Legro Richard S, Dunaif Andrea

Abstract excerpt

OBJECTIVE: We performed this study to test the hypothesis that variation in the lamin a/c gene (LMNA) contributes to milder phenotypes of insulin resistance, hyperandrogenism, and/or metabolic syndrome associated with polycystic ovary syndrome (PCOS). RESEARCH DESIGN AND METHODS: We resequenced the coding region, flanking intronic, and proximal promoter regions of the lamin a/c gene in 43 women with PCOS with...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Case-Control Studies
Share to DNA Mutational Analysis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Frequency

Share to Lamin Type A

Share to Linkage Disequilibrium

Share to Polycystic Ovary Syndrome

Share to White People

Share to Young Adult

Source

Open in PubMed Open full text

Identifiers

PMID: 19401371
DOI: 10.1210/jc.2008-2704
PMCID: PMC2708953

Genes

LMNA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The role of genetic variation in the lamin a/c gene in the etiology of polycystic ovary syndrome.PMID 19401371Read ↗

The Role of Genetic Variation in the Lamin A/C Gene in the Etiology of Polycystic Ovary SyndromeSemantic proximity Read ↗

Lamin A/C polymorphisms, type 2 diabetes, and the metabolic syndrome: case-control and quantitative trait studies.Semantic proximity Read ↗

Common variation in LMNA increases susceptibility to type 2 diabetes and associates with elevated fasting glycemia and estimates of body fat and height in the general population: studies of 7,495 Danish whites.Semantic proximity Read ↗

Variation in the lamin A/C gene: associations with metabolic syndrome.Semantic proximity Read ↗

LMNA rs4641 and the muscle lamin A and C isoforms in twins--metabolic implications and transcriptional regulation.Semantic proximity Read ↗

Common variation in the LMNA gene (encoding lamin A/C) and type 2 diabetes: association analyses in 9,518 subjects.Semantic proximity Read ↗

Analysis of the lamin A/C gene as a candidate for type II diabetes susceptibility in Pima Indians.Semantic proximity Read ↗

The inflammatory gene pathway is not a major contributor to polycystic ovary snydrome.Semantic proximity Read ↗

The Role of Gene Alterations in the Pathogenesis of Polycystic Ovary SyndromeSemantic proximity Read ↗

Polycystic ovary syndrome is not associated with genetic variants that mark risk of type 2 diabetes.Semantic proximity Read ↗

Type A insulin resistance syndrome revealing a novel lamin A mutation.Semantic proximity Read ↗

A C/T single nucleotide polymorphism at the tyrosine kinase domain of the insulin receptor gene is associated with polycystic ovary syndrome.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.