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Article

Analysis of the lamin A/C gene as a candidate for type II diabetes susceptibility in Pima Indians.

Diabetologia - 1 Jun 2001

Wolford J K, Hanson R L, Bogardus C, Prochazka M

Abstract excerpt

AIMS/HYPOTHESIS: Lamin A/C (LMNA) is located within a region on chromosome 1q that has been linked with Type II (non-insulin-dependent) diabetes mellitus in Pima Indians. Rare mutations in exon 8 of LMNA underlie Dunnigan-Type familial partial lipodystrophy, a disease characterized by regional ad...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 11440372
DOI: 10.1007/s001250051688

Genes

LMNA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-11440372-2026-09-02.1. Manifest publication-graph-cohort-2026-09-02.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

Analysis of the lamin A/C gene as a candidate for type II diabetes susceptibility in Pima Indians.PMID 11440372Read ↗

Lamin A/C polymorphisms, type 2 diabetes, and the metabolic syndrome: case-control and quantitative trait studies.Semantic proximity Read ↗

Association between nuclear lamin A/C R482Q mutation and partial lipodystrophy with hyperinsulinemia, dyslipidemia, hypertension, and diabetes.Semantic proximity Read ↗

Common variation in the LMNA gene (encoding lamin A/C) and type 2 diabetes: association analyses in 9,518 subjects.Semantic proximity Read ↗

Assessment of established HDL-C loci for association with HDL-C levels and type 2 diabetes in Pima Indians.Semantic proximity Read ↗

Variants in ACAD10 are associated with type 2 diabetes, insulin resistance and lipid oxidation in Pima Indians.Semantic proximity Read ↗

Chromosome 4q locus associated with insulin resistance in Pima Indians. Studies in three European NIDDM populations.Semantic proximity Read ↗

Variants in the Ca V 2.3 (alpha 1E) subunit of voltage-activated Ca2+ channels are associated with insulin resistance and type 2 diabetes in Pima Indians.Semantic proximity Read ↗

The role of insulin receptor substrate-1 gene (IRS1) in type 2 diabetes in Pima Indians.Semantic proximity Read ↗

An autosomal genomic scan for loci linked to prediabetic phenotypes in Pima Indians.Semantic proximity Read ↗

Subcutaneous abdominal adipocyte size, a predictor of type 2 diabetes, is linked to chromosome 1q21--q23 and is associated with a common polymorphism in LMNA in Pima Indians.Semantic proximity Read ↗

An autosomal genomic scan for loci linked to type II diabetes mellitus and body-mass index in Pima Indians.Semantic proximity Read ↗

An LMNA variant is associated with dyslipidemia and insulin resistance in the Japanese.Semantic proximity Read ↗

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