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The Role of Gene Alterations in the Pathogenesis of Polycystic Ovary Syndrome

12 May 2025

Abstract excerpt

Family studies have shown that polycystic ovary syndrome (PCOS) has probable genetic transmission because of a high incidence of relatives who present clinical or biochemical characters of the syndrome. However, initial candidate gene studies were unsuccessful. Genome wide association studies (GWASs) have shown that at least 29 gene alterations are common in PCOS, but it has been calculated that the altered genes...

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PMID: 40429342
DOI: 10.3390/jcm14103347

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