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The apoptosis linked gene ALG‐2 is dysregulated in tumors of various origin and contributes to cancer cell viability

19 Aug 2007

Abstract excerpt

The apoptosis linked gene-2 (ALG-2), discovered as a proapoptotic calcium binding protein, has recently been found upregulated in lung cancer tissue indicating that this protein may play a role in the pathology of cancer cells and/or may be a tumor marker. Using immunohistochemistry on tissue microarrays we analysed the expression of ALG-2 in 7371 tumor tissue samples of various origin as well as in 749 normal...

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PMID: 19383317
DOI: 10.1016/j.molonc.2007.08.002

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