Article
Two forms of the apoptosis-linked protein ALG-2 with different Ca(2+) affinities and target recognition.
The Journal of biological chemistry - 7 Apr 2000
Tarabykina S, Møller A L, Durussel I, Cox J, Berchtold M W
Abstract excerpt
The apoptosis-linked gene ALG-2 encodes a Ca(2+)-binding protein of the penta EF-hand family. To investigate the Ca(2+) binding properties of the recombinant ALG-2 protein, we have cloned ALG-2 cDNA from mouse liver mRNA. Sequence analysis showed that two types of clones were present. One (named ALG-2,5) corresponds to the published ALG-2 sequence (Vito, P., Lacana, E., and D'Adamio, L. (1996) Science 271,...
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