Article

The Molecular Mechanism of ALG-2 in Regulating Proliferation, Migration, and Epithelial- Mesenchymal Transition in Oral Squamous Cell Carcinoma

2025-11-27

Abstract excerpt

<title>Abstract</title> <p> <bold>Objective:</bold> This study aimed to investigate the expression characteristics of apoptosis-linked gene-2 (ALG-2) in oral squamous cell carcinoma (OSCC) tissues and cells, its impact on malignant cell behaviors, and its potential molecular mechanisms by integrating bioinformatics and experimental approaches. The goal was to assess whether ALG-2 could provide a theoretical bas...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: e4a94a27-64b8-5e93-b234-1b118452fb77
DOI: 10.21203/rs.3.rs-7828746/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

The Molecular Mechanism of ALG-2 in Regulating Proliferation, Migration, and Epithelial- Mesenchymal Transition in Oral Squamous Cell CarcinomaDOI 10.21203/rs.3.rs-7828746/v1Read

Proliferation and Apoptosis Pathways and Factors in Oral Squamous Cell CarcinomaSemantic proximity Read

A 3-mRNA-based prognostic signature of survival in oral squamous cell carcinomaSemantic proximity Read

Screening biomarkers of oral leukoplakia canceration based on GEO database and in vitro experimentsSemantic proximity Read

Profiling Expression of Brac2 Gene in Cases of Oral Squamous Cell Carcinoma and Oral Potentially Malignant Disorders-a Pilot Study.Semantic proximity Read

The apoptosis linked gene ALG‐2 is dysregulated in tumors of various origin and contributes to cancer cell viabilitySemantic proximity Read

ALG3 Contributes to the Malignant Biological Properties of Oral Squamous Cell Carcinoma Cells Through Regulating CDK-Cyclin PathwaySemantic proximity Read

Title: LAMC2 promotes oral squamous cell carcinoma growth by activating the p-ERK/c-Myc signaling pathwaySemantic proximity Read

ANO1 promotes malignant progression and epithelial–mesenchymal transition in head and neck squamous cell carcinoma through ERK/YAP-associated signalingSemantic proximity Read

Two stem cell markers, ATP‐binding cassette, G2 subfamily (ABCG2) and BMI‐1, predict the transformation of oral leukoplakia to cancerSemantic proximity Read

The role of apoptosis in oral disease: Mechanisms; aberrations in neoplastic, autoimmune, infectious, hematologic, and developmental diseases; and therapeutic opportunitiesSemantic proximity Read

Long Non-Coding RNA AC022306.2 Promotes Cell Proliferation, Migration, and Invasion by Mediating GALK2 in Epithelial Ovarian CancerSemantic proximity Read

Study on the mechanism of KIF2C/PLK1 in the growth and metastasis of oral squamous cell carcinomaSemantic proximity Read