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ILP-2: A New Bane and Therapeutic Target for Human Cancers

23 Jun 2022

Abstract excerpt

Inhibitor of apoptosis protein-related-like protein-2 (ILP-2), also known as BIRC-8, is a member of the inhibitor of apoptosis protein (IAPs) family, which mainly encodes the negative regulator of apoptosis. It is selectively overexpressed in a variety of human tumors and can help tumor cells evade apoptosis, promote tumor cell growth, increase tumor cell aggressiveness, and appears to be involved in tumor cell...

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PMID: 35814477
DOI: 10.3389/fonc.2022.922596

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