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Article

Global variation in CYP2C8-CYP2C9 functional haplotypes.

The pharmacogenomics journal - 1 Aug 2009

Speed William C, Kang Soonmo Peter, Tuck David P, Harris Lyndsay N, Kidd Kenneth K

Abstract excerpt

We have studied the global frequency distributions of 10 single nucleotide polymorphisms (SNPs) across 132 kb of CYP2C8 and CYP2C9 in approximately 2500 individuals representing 45 populations. Five of the SNPs were in noncoding sequences; the other five involved the more common missense variants (four in CYP2C8, one in CYP2C9) that change amino acids in the gene products. One haplotype containing two CYP2C8...

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Identifiers

PMID: 19381162
DOI: 10.1038/tpj.2009.10
PMCID: PMC2782405

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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